SaniSurface® Whitepaper

How do SaniSurface® Germ-free stickers provide protection against cross-contamination?

All SaniSurface® products harness the excellent Antimicrobial technology of Rambo Guard TM-Revolutionary Antimicrobial Bonding. This long-lasting nanotechnology is molecularly infused on to the surface of the plastic sheet. It generates an invisible cross link effect that traps the pathogens and kills them instantly.

Where can these Germ-free sticker stickers be used?

SaniSurface® Germ-free stickers are designed to be used on any surface that requires protection against germ and people touch. They can be used on door handles, railings, pin pads, elevator button panels, card-swiping machines, shopping cart handles, luggage handles, toilet handles, TV remote controls, Slot Machines, ATM button consoles, Vending machine panels and so much more.

How long do the anti-germ coating last on the stickers?

SaniSurface® provides an antimicrobial germ-free surface to touch and can be cleaned with water and a cloth. Tape and covers should be replaced every 90 days with normal traffic. Heavy traffic requires more frequent changes. The tape is effective for about 1500 grips, touches or holds.  When it is time to replace, just peel off, clean any adhesive residue, and stick on a new one. In household applications, they must be replaced every three months. In offices, condos/ Apartment complexes and hotels, every two weeks. In high traffic public place applications such as ATMs, elevator panels, carts, railings, and pin pad machines, it is recommended that they are replaced once a week.

The thumb-rule is: - Home usage: 3 months; Commercial Usage: 1 month; High usage: airports / stadiums / theaters / grocery stores / malls/ hotels: 1 week

Why are SaniSurface® Sticker so Important?

Contact surface areas in a public building or a healthcare facility are susceptible to not only pandemic-related viruses but also the proliferation of such infectious pathogens that survive on inanimate objects. Surfaces such as elevator panels, door handles, ramps, and common utility areas are the breeding grounds of such challenging Multi Drug-Resistant Germs.

SaniSurface® offers comprehensive products & solutions to address this intractable problem. SaniSurface® protection stickers remain germ-free always as that constantly destroy the germs, giving you a safe and secure surface to touch.  

This Ready-to-use (RTU) products are designed to act as effective tools to be incorporated into any Integrated Preventive Sanitation Program by healthcare facilities, community centers, and corporations globally. 

Areas in and Around Hospitals are even worse!

Nearly 10% of the patients are subjected to Hospital Acquired Infections. This percentage is higher in the visitors or patient attendants. Hospital-Acquired Infection (HAI) or Nosocomial infection is due to Multi Drug-Resistant Super Bugs such as MRSA (Methicillin-resistant Staphylococcus aureus, ORSA (Oxacillin-resistant Staphylococcus aureus), and VRSA (Vancomycin-resistant Staphylococcus aureus) are very lethal as they do not respond to antibiotics and are associated with an increased risk of infection, morbidity, and mortality. The challenge is increasing as these pathogens rapidly mutate and spread.

To keep surfaces areas germ-free. Keep them protected with SaniSurface®

Are SaniSurface® sticker stickers safe?

100% - Rambo Guard TM technology has been tested by Biotesting Services Lab- an NABL certified lab for Cytotoxicity and skin-irritation. SaniSurface® products are nontoxic, non-allergen, and they are of course eco-friendly.

Which labs have tested the antimicrobial function on these sticker stickers?

They are tested at both internationally renowned and certified labs for their outstanding features. More than 99% kill-ratio on both Gram positive and Gram-negative pathogens:

Tested by SGS and TTH Non-allergen and Non-Toxic: Biotesting Services, a premium NABL-certified lab

SGS has tested the technology for applications on doormats of other plastic products and TTH, an NABL (National Accreditation Board for Testing Laboratories) certified lab has tested it on our plastic stickers.

SaniSurface® Stickers are currently being tested in an Antimicrobial Accredited Testing Facility in Chicago.

How are these adhesive stickers removed and disposed of?

Unwrap and remove

Use a safe box-cutter or knife gently to cut the tape if needed

Do not cut deep to avoid touching and scratching the surface of the object

After removal, dispose in ‘non-recyclable’ trash bins

 

How does the technology behind SaniSurface® work?

Disease-causing-Germs are broadly classified as Bacteria, Viruses and Fungi. These pathogens or microbes either mutate and become drug-resistant or new types break out, precipitating global pandemics. Hygienic lifestyle is the most important factor in infection-prevention measures. Adoption of products and practices that enhance personal protection is an essential element of the new safe protocol.

This finds more relevance in the recent times, as global pandemics wreak havoc, warranting strict hygiene regimes. Leveraging our unique, robust suite of long-lasting antimicrobial, hybrid filtration and substrate technologies, we created SaniSurface® Stickers.

Our developer has pioneered engineering innovation, to create a wide range of infection-controlling and disease-prevention consumer products and solutions.

All SaniSurface® products harness the excellent Antimicrobial efficacy of Rambo Guard TM – Revolutionary Antimicrobial Bonding. This nanotechnology (controlling matter on the atomic and molecular scale) is molecularly infused (creates a bond) on to the surface of the substrate (sticker). It generates an invisible cross link effect (a chemical bond between different chains of atoms in a polymer or other complex molecule) that traps the pathogens and kills them physically.

 

What makes the technology effective against COVID-19?

The technology creates a robust positive-charged antimicrobial layer on SaniSurface® products that constantly destroy both the lipid bilayer and the negative components of COVID-19.

 

What is the architecture of COVID-19?

COVID-19 (alias) Nova-Coronavirus is an alphavirus enveloped with a genome of a single strand of positive-sense RNA. COVID-19 has 4 distinct constituents: The key RNA, which is highly charged, the N- M-E protein matrix i.e. Nucleocapsid-Membrane-Envelope, the Spike Glycoprotein and HE - Hemagglutinin-esterase Dimer. Whereas the single-strand RNA is the virion, the N-M-E proteins give the structural stability and protection to the virus. The S and HE are functional ones for invading the host cells, receptor binding and endocytosis.

Coronavirus acquires its lipid envelope from host’s cellular membranes through budding process, because it needs to leave the membrane of the host intact for the host to survive. Since it is an Alphavirus it does not tolerate dominance of host proteins and selectively dominates the virion content involving specific association of viral membrane proteins, glycoproteins, and capsid protein, together with the viral genomic RNA, into a virus particle. On the other hand, they need to avoid the host immune system. So, they absorb the phospholipids and proteins from the host cell membranes.

Rambo Guard TM uses an EPA registered pesticide as active ingredient to create a host of antimicrobial consumer products that destroys COVID-19 virus. The technology triggers dissociation of lipid bilayers and disruption of intermolecular interactions between Membrane protein and S protein through ion-abnegation and creation of hydrophobic spike to puncture the polar- head region of lipid molecule.

What are the negative components of COVID-19 virus that makes it destructible?

COVID-19 has two extremely vulnerable components – the S-protein and the M-protein.

 

S-Protein

The spike (S) protein is the sole viral membrane protein responsible for cell entry. It binds to the receptor on the target cell and mediates subsequent virus-cell fusion. Spikes can be seen under the electron microscope as clear, 20-nm-long, bulbous surface projections on the virion membrane. The Receptor binding part is a Negatively Charged Spike Peptide.

 

Structural components of SARS-CoV spike glycoprotein and expression construct. L denotes the leader peptide (residues 1 to 13). The cDNA fragments encompassing the full-length spike coding sequence and the spike sequence with deletions of the TM and Cys-rich regions were cloned into an expression vector, pCMVIII, to create nSh and nSh TC, respectively. All proteins were tagged with six histidine residues at the end of the C terminus. (B) Schematic diagram of SARS-CoV spike glycoprotein, which is NEGATIVE.

 

M-Protein

 

 

Amino acid properties are indicated: hydrophobic (red), hydrophilic (blue), polar, CHARGED (asterisks). Trans Membrane Domain consists of the two nonpolar, neutral amino acids, valine, and leucine, lending a strong hydrophobicity to the E protein. The middle region of the peptide is uncharged and flanked on one side by the negatively charged amino (N)-terminus, and, on the other side, the carboxy (C)- terminus of variable charge. Only 2 specific Amino acids are found that are POSITIVE.

What about Competitors?

There are two competitors to our technology, but both over promise and under-deliver compared to SaniSurface®.

1). One that uses Nano-Titanium Dioxide 

This Competitor uses Titanium Dioxide Nano Particles that triggers action only in the presence of direct sunlight.  They have cleverly mentioned the active ingredient as a ‘Mineral’ to avoid the stigma associated with Titanium Dioxide.

TiO2 is a substance that oxidizes Volatile Organic Compounds and is designed to neutralize the pollutants and toxins such as Nitrogen Oxide, Carbon Monoxide, and Sulfur Dioxide. The antibacterial feature is actually the secondary function of this product, the primary being self-cleaning, which is why they have cleverly created an illusion that their products are ‘anti-septic’ using branding, but in their sales pitch, they claim ‘Self Cleaning’ and not ‘Self-Sanitizing’.

The major drawbacks of their technology are:
Their technology works only in the presence of direct sunlight with sufficient Ultraviolet rays. The functionality is directly proportional to the amount of sunlight these stickers directly receive. The maximum amount of kill-ratio is up to 70% under direct sunlight and far less under artificial lighting.
The Nanoparticles of TiO2 pose a grave bio-hazard to plant and animal life and even after disposal cause a serious threat to the soil quality and ecology.  Nevertheless, the EPA has cleared its usage for water treatment, skin creams. To our knowledge, it has not been cleared for surface usage, as it is a potential carcinogen in bio concentrated scenarios
 
2). One that uses Silver as the antimicrobial
Silver antimicrobial is considered hazardous, resulting in EPA repealing the approval

A federal appeals court in California has revoked the Environmental Protection Agency’s (EPA) conditional approval of a nanosilver product used in a wide range of consumer products as an antimicrobial agent.

“The US Court of Appeals for the Ninth Circuit concluded that the agency’s conditional approval of Nanosilver was based on two unsubstantiated assumptions. The EPA had argued that current users of conventional silver biocides would replace them with Nanosilva, and that the product’s incorporation into new products would decrease the amount of silver released into the environment.”

Until more studies are conducted, and findings reported, nanosilver will have to wait. Some think it may be safe, but others think it will be more harmful. We need more studies and more facts before we can tell for sure.

Jennifer Sass, senior scientist with the health program of the Natural Resources Defense Council says of the court’s decision: “This is an important victory for public health. Nanosilver is known to be highly toxic to aquatic life and may be hazardous to people. EPA rushed to judgment by approving it, leaving consumers to be guinea pigs. Now the agency must take a closer look at its potential to cause harm.”


https://www.microban.com/blog/approval-of-nanosilver-antimicrobial-repealed
https://scipol.duke.edu/track/california-federal-court-rules-conditional-registration-nanosilver-containing-pesticidev

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